HC, PHPV & L2 Hydroxyglutaric AciduriaEye Conditions HC & PHPV
For many years now the breed has been aware of two hereditary eye conditions, HC (Hereditary Cataract) and PHPV (Persistent Hyperplastic Primary Vitroeus) It is known that HC is inherited by an autosomal
recessive path (i.e. that both parents must be carriers of the defective gene to produce affected offspring). HC is a progressive condition and this means that although the puppy is not born with cataracts they will
start to develop at a juvenile stage (maybe from 8 months onwards) and will progress until the dog is totally blind. The condition is bi-lateral, meaning that it will affect both eyes equally The mode of
inheritance for PHPV is not so clear, but it is known that it is a congenital condition (present at birth) and that it is not progressive. This means that if a puppy is born with PHPV it can be detected by ophthalmic
screening from 6 weeks of age and if it is affected, whatever the condition of the problem at that stage it will not change throughout the dog's life Either condition can be operated on but it is a
serious operation, obviously quite traumatic and expensive. It is not always covered by pet insurance due to the hereditary nature NEUROLOGICAL CONDITION - L2-HGA (L2 hydroxyglutaric aciduria) In the past few
years a number of Staffords have been diagnosed with a metabolic disorder; its clinical title is L-2 hydroxyglutaric aciduria or L-2 HGA. This condition has manifested itself in varied ways with dogs exhibiting
behaviour changes and dementia (staring at walls, getting stuck under tables and in corners, loss of obedience and house training), anxiety states, having full blown seizures, as well as exercise intolerance, ataxia
(unsteady gait), tremors and muscular stiffness. Dogs from differing bloodlines have been found to be sufferers and the number of affected dogs diagnosed has risen CLICK HERE TO FIND OUT MORE AND TO GET YOUR DOG TESTED. BE A RESONSIBLE BREEDER AND GET THE RELEVANT TESTS DONE,
SO YOU DON'T PASS IT ON. |
